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Clarity Science – O.P.T.I.M.A.G – Pain Study

O.P.T.I.M.A. – G stands for Observing Pain Transdermal Treatments – Improving and Managing All GI Symptoms. This is study from Clarity Science for patients who have been prescribed a topical/transdermal pain medication.

Published April 20, 2024 Updated May 29, 2025 2 min read

Clarity Science- O.P.T.I.M.A.G - Pain Study

Written by Nevada Advanced Pain Specialists staff

clinical trial

O.P.T.I.M.A. – G stands for Observing Pain Transdermal Treatments – Improving and Managing All GI Symptoms. This is study from Clarity Science for patients who have been prescribed a topical/transdermal pain medication. The study aims to evaluate their experiences and perceptions. Pain and other related symptoms will be evaluated by patient feedback.

In 2016, the Center for Diseases Control (CDC) released strict guidelines for prescribing opioids in an effort to decrease overdoses and unintentional deaths linked to the misuse of opioids. This cream is an exciting alternative to opioids for the treatment of pain.

Potential benefits of topical/transdermal pain medication:
• May be effective for patients with acute and chronic pain
• May be used for multiple diagnoses and may include multiple medications to treat different types of pain
• May reduce or avoid side effects and complications associated with oral pain medications
• May decrease diversion, addiction, and abuse inherent with oral narcotic drugs
• May reduce or eliminate the use of oral pain medications
• May be used in conjunction with oral medications

The following is the inclusion/exclusion criteria for the study:
• Male or female, ages 18-64
• Participants must have insurance coverage for prescribed medications
• Have received a prescription for a topical pain formulation from their treating physician
• No beneficiaries of government funded healthcare programs
• Signed Informed Consent authorization and HIPAA Release form

Clarity Science, based out of Austin, Texas is a “leading international scientific research organization that performs rigorous research in the field of healthcare across a myriad of therapeutic areas, including pain.”

Their newest study, TARGET, is a study on topical silicone in restoring scars and burn tissue. This is an Institutional review board-approved observational study being conducted by Clarity to study the effectiveness of topical/transdermal treatments for scar/burn characteristics, symptoms, and patient perceptions. Clarity is looking for participants in their study.

The following is the inclusion/exclusion criteria for the study:
• For patients who have scar tissue – including new scars, old scars, surgical scars, keloids, burn scars, and stretch marks – and other skin conditions
• Male or female, ages 6-64
• Participants must have insurance coverage for prescribed medications
• No beneficiaries of government funded healthcare programs
• Signed informed Consent authorization and HIPAA Release form

If you meet the criteria for the TARGET Scar Tissue Study or the O.P.T.I.M. A. – G Pain Study and are interested in participating, talk to your provider, call 1 (800) 616-9403, or visit www.clarityscience.com

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